Will taking dydrogesterone tablets stop bleeding in patients with endometrial cancer?

In general, patients with endometrial cancer may experience hemostasis (stoppage of bleeding) after taking dydrogesterone tablets. The detailed analysis is as follows:

Dydrogesterone is a progestin medication primarily used to treat conditions caused by insufficient endogenous progesterone, such as dysmenorrhea, endometriosis, secondary amenorrhea, irregular menstrual cycles, dysfunctional uterine bleeding, premenstrual syndrome, threatened or habitual abortion due to progesterone deficiency, and infertility due to luteal phase defect. Endometrial cancer is a malignant tumor arising in the endometrium, and patients may present symptoms including irregular vaginal bleeding, abnormal vaginal discharge, and abdominal discomfort. Taking dydrogesterone tablets can promote thickening of the endometrium, thereby helping to stop bleeding. Additionally, the progestogen component in dydrogesterone enhances the activity of the coagulation system, increasing the synthesis and release of clotting factors, thus reducing vascular leakage and bleeding in the endometrium. Therefore, dydrogesterone tablets can help control bleeding in patients with endometrial cancer.

It should be noted that dydrogesterone tablets must be used under the guidance of a physician and should not be taken without medical supervision to avoid potential adverse effects.