Is a urinary microalbumin level of 30.5 mg/24h severe?

Jul 29, 2023 Source: Cainiu Health
Dr. Zhao Xinju
Introduction
In general, the clinically defined normal range for microalbuminuria is less than 30 mg/24h. A urinary microalbumin level of 30.5 mg/24h may be caused by normal physiological factors and is usually not serious; however, if it results from pathological causes, it could be more concerning. In summary, a microalbumin level of 30.5 mg/24h is considered slightly elevated.

Under normal circumstances, the clinical reference range for urinary microalbumin is less than 30 mg/24h. A result of 30.5 mg/24h may be caused by normal physiological factors and is generally not serious. However, if it is due to pathological causes, the condition may be more severe. The specific analysis is as follows:

1. Not Serious

Physiological factors such as intense physical exercise or fever may also lead to elevated levels of urinary microalbumin. Usually, no special treatment is required, and the urine protein typically returns to negative spontaneously after rest.

2. Serious

Albumin is one of the important plasma proteins. Due to its large molecular size, it normally cannot pass through the glomerular basement membrane, which is why only trace amounts are found in the urine of healthy individuals. When diseases such as glomerulonephritis, cystitis, or pyelonephritis occur, damage to the glomeruli alters their permeability, increasing the permeability of the glomerular basement membrane and allowing albumin to leak into the urine. In such cases, the condition is considered relatively serious.

In summary, although a microalbumin level of 30.5 mg/24h represents only a mild elevation, the severity depends on the underlying cause. Therefore, when test results are abnormal, it is important to consult a physician for further evaluation and diagnosis.