Which is better: recombinant human interferon α1b or α2b?
Jul 30, 2023
Source: Cainiu Health
Dr. Jiang Weimin
Introduction
Both recombinant human interferon α1b and α2b are effective; the choice should be based on individual circumstances. Recombinant human interferon α1b and recombinant human interferon α2b are both types of recombinant human alpha interferons, possessing antiviral, antitumor, and immunomodulatory effects. Recombinant human interferon α1b is derived from white blood cells of healthy individuals in China and belongs to the interferon α1b subtype.
Generally, both recombinant human interferon α1b and α2b are effective; the choice should be based on individual circumstances. The detailed analysis is as follows:
Recombinant human interferon α1b and recombinant human interferon α2b are both types of recombinant human alpha interferons, possessing antiviral, antitumor, and immunomodulatory effects. Recombinant human interferon α1b is derived from white blood cells of healthy individuals in China and belongs to the α1b subtype of interferon. It demonstrates better efficacy in the domestic population and is less likely to induce neutralizing antibodies, making it suitable for treating chronic hepatitis B and chronic hepatitis C. In contrast, recombinant human interferon α2b originates from interferon produced by infected individuals abroad and belongs to the α2b subtype, which may be more suitable for foreign populations. Additionally, recombinant human interferon α1b is a domestically produced drug with a lower price, whereas recombinant human interferon α2b is imported and relatively more expensive. Both recombinant human interferon α1b and α2b can be used to treat malignant tumors and viral infections; therefore, both are considered effective options.
If considering the use of recombinant human interferon α1b or α2b, it is recommended to do so under the guidance of a physician to avoid compromising therapeutic effectiveness.
