Why does the pain go away after taking analgesics?

The pain usually subsides after taking analgesic tablets, primarily because these medications reduce the sensitivity of local nerves. The detailed explanation is as follows:

Analgesic tablets belong to the class of antipyretic and analgesic drugs, with main active ingredients including phenobarbital, phenacetin, and aminopyrine. After being digested and absorbed by the body, these components enter the bloodstream via blood vessels and circulate directly into the brain. They reduce the synthesis of prostaglandins and also directly suppress the excitability of sensitive local nerves. This is why pain symptoms improve after taking analgesic tablets. However, since these are non-steroidal anti-inflammatory drugs (NSAIDs), excessive use may lead to dysfunction of the central nervous system, causing prolonged abnormal excitation, as well as gastrointestinal irritation resulting in discomforts such as bloating and vomiting. Therefore, patients should take these medications only under medical supervision.

Patients with kidney or liver disease are advised not to take analgesic tablets and should follow their doctor's instructions to select alternative medications.