Does empagliflozin tablets damage the liver and kidneys?

Aug 01, 2023 Source: Cainiu Health
Dr. Li Ping
Introduction
Empagliflozin tablets generally do not harm the liver or kidneys; however, long-term or excessive use may cause liver or kidney damage. The detailed analysis is as follows: Empagliflozin tablets are primarily used to treat diabetes. After the drug's components enter the body, they promote the excretion of glucose through the glomeruli, allowing a large amount of glucose to be eliminated from the body via urine instead of re-entering the plasma. When taken according to medical instructions, empagliflozin tablets are safe and effective.

Empagliflozin tablets generally do not harm the liver or kidneys, but long-term or excessive use may cause liver and kidney damage. The specific analysis is as follows:

Empagliflozin tablets are primarily used to treat diabetes. After the drug enters the body, it prevents glucose from being reabsorbed by the glomeruli, allowing excess glucose to be excreted in urine rather than returning to the bloodstream. When taken according to medical instructions, empagliflozin usually does not harm the liver or kidneys. Moreover, when taken together with metformin hydrochloride sustained-release tablets, it can significantly enhance blood glucose-lowering effects.

However, if patients take empagliflozin for prolonged periods or in excessive doses, the liver may be exposed to continuous stimulation from the drug components. Additionally, the kidneys may become overburdened during glucose reabsorption, potentially impairing normal kidney function. In severe cases, this may lead to conditions such as pyelonephritis or renal failure. Therefore, patients taking this medication should undergo regular full-body checkups.

To avoid bodily harm, it is recommended to use this medication under a doctor's supervision. If any adverse symptoms occur, discontinue the drug immediately and seek medical attention promptly.