What diseases could cause leg weakness and lack of strength?

Generally, leg weakness and lack of strength may be caused by excessive fatigue, lumbar disc herniation, lower extremity varicose veins, arterial thrombosis, brain tumors, and other conditions. A detailed analysis is as follows:

1. Excessive Fatigue

If the body is overly fatigued, it may lead to muscle strain in the legs, resulting in leg weakness. This may also cause muscle soreness. In such cases, symptoms can usually be relieved with adequate rest.

2. Lumbar Disc Herniation

Lumbar disc herniation is caused by degenerative changes in the intervertebral discs. If the condition is severe, it may compress nerves in the lower limbs, causing weakness, along with pain and numbness. Treatment may include medications such as meloxicam tablets or celecoxib capsules under a doctor's guidance.

3. Lower Extremity Varicose Veins

Lower extremity varicose veins are primarily caused by impaired venous blood return. They can not only cause leg heaviness, swelling, and weakness, but may also lead to local swelling, pain, and warmth. Medications such as micronized purified flavonoid fraction (MPFF) tablets or diosmin tablets may be used under medical supervision.

4. Arterial Thrombosis

Normal blood circulation is essential for delivering nutrients throughout the body. When a blood clot forms in the leg, circulation is disrupted, potentially depriving the limb of sufficient nutrition and oxygen, thereby impairing tissue function and causing the patient to feel weak. Treatment may include anticoagulant or antiplatelet medications such as enteric-coated aspirin tablets or clopidogrel hydrogen sulfate tablets, taken as prescribed by a physician.

5. Brain Tumor

A brain tumor is a growth within the skull and is a relatively common condition in neurosurgery. Symptoms may include headache, vomiting, edema, generalized weakness, and limb numbness. Treatment may involve targeted therapy drugs such as imatinib mesylate tablets or gefitinib tablets, taken according to medical advice.

Patients are advised to seek timely medical evaluation at a hospital, undergo appropriate diagnostic tests under medical guidance, identify the underlying cause, and receive systematic and standardized treatment.