Causes of Lower Eyelid Twitching
Lower eyelid twitching is a relatively prominent manifestation of eyelid myokymia. Eyelid myokymia is generally caused by eye strain, periorbital inflammation, or irritation of the sympathetic nerves around the eyes. Eyelid twitching can cause significant discomfort and inconvenience. So, what are the specific causes of lower eyelid twitching? Below, we provide a detailed explanation.

Causes of Lower Eyelid Twitching
1. Eye Strain
Excessive use of the eyes—especially when accompanied by general bodily discomfort—can trigger involuntary contractions of the eyelid muscles, resulting in “eye twitching.” This type of twitching is typically due to heightened activity in the sympathetic nerves that control the eyelid muscles. Such twitching is usually sporadic, occurring once or two to three times per day, with each episode lasting one to several seconds. In most cases, no medication is required; symptoms typically resolve or subside following adequate rest.
2. Periorbital Inflammation
In some cases, eyelid twitching may be accompanied by additional symptoms such as gritty or sandy sensations in the eyes and conjunctival redness. These symptoms often result from periorbital inflammation—for example, conjunctivitis or trachoma. Treatment with topical antibiotics such as rifampicin eye drops or levofloxacin eye drops usually leads to symptom resolution.

3. Meningitis
Meningitis is a serious, potentially life-threatening condition. When meningitis develops, abnormalities may occur in brain structures—including the substantia nigra—and in neural pathways controlling the orbicularis oculi muscle. Consequently, some patients experience involuntary eyelid spasms. Attempting to forcefully close the eyes may exacerbate symptoms; therefore, prompt medical evaluation and management are essential.
4. Facial Spasm (Hemifacial Spasm)
When experiencing eyelid twitching, individuals should also observe whether facial muscle spasms are present. Facial spasm—a neurological disorder involving involuntary contractions of facial muscles—can manifest as persistent eyelid twitching. While many people dismiss this as a benign, transient physiological phenomenon requiring only rest, persistent, recurrent twitching warrants clinical evaluation to rule out hemifacial spasm.

The above outlines the primary causes of lower eyelid twitching. We hope this information proves helpful.