Elevated alpha-1 microglobulin

α1-microglobulin is primarily synthesized by the liver and may increase during acute inflammation or infection. Generally, elevated α1-microglobulin levels could be caused by glomerulonephritis, lupus nephritis, nephrotic syndrome, diabetic nephropathy, or hypertensive nephropathy. These conditions can be improved through general management, medication, and other treatments. Specific analyses are as follows:

1. Glomerulonephritis: This may result from infection and commonly causes facial edema, severe eyelid swelling, oliguria, and other symptoms, leading to the aforementioned test abnormalities. Under medical guidance, patients may use medications such as furosemide injection or erythromycin tablets for treatment.

2. Lupus nephritis: Often associated with autoimmune system disorders, it frequently leads to heavy proteinuria, edema, and other symptoms, resulting in elevated α1-microglobulin levels. Under medical supervision, patients may be treated with medications such as methylprednisolone tablets or cefixime granules.

3. Nephrotic syndrome: This may be triggered by metabolic abnormalities, infections, or other factors, commonly causing oliguria, edema, nausea, vomiting, and other symptoms, resulting in increased α1-microglobulin levels. Under a doctor's guidance, patients may use medications such as bumetanide tablets or furosemide injection for treatment.

4. Diabetic nephropathy: A kidney complication caused by diabetes, it may lead to hypertension, edema, and other symptoms, resulting in elevated α1-microglobulin levels. Under medical direction, patients may use medications such as insulin glargine injection or nifedipine tablets for treatment.

5. Hypertensive nephropathy: Mainly caused by long-standing hypertension leading to target organ damage in the kidneys. Early signs include increased nocturnal urination and elevated α1-microglobulin levels. Under medical guidance, patients may use medications such as bisoprolol fumarate tablets or verapamil hydrochloride tablets for treatment.

During treatment, patients should maintain a light diet, avoid excessive fluid intake, and engage in appropriate physical exercise.