Will taking Biktarvy lead to drug resistance?

Biktarvy usually refers to Bictegravir Emtricitabine Tenofovir Disoproxil Fumarate tablets. Whether drug resistance may develop when taking Bictegravir Emtricitabine Tenofovir Disoproxil Fumarate generally depends on specific circumstances. Resistance typically does not occur if the medication is taken as prescribed by a physician; however, improper use of the drug may lead to resistance. Detailed analysis is as follows:

1. No resistance: Bictegravir Emtricitabine Tenofovir Disoproxil Fumarate tablets are used to treat adult patients with human immunodeficiency virus type 1 (HIV-1) infection and belong to antiviral drugs that can inhibit replication of HIV-1. If patients take the medication according to medical advice, resistance generally will not develop.

2. Resistance possible: If patients with the aforementioned viral infection self-medicate with Bictegravir Emtricitabine Tenofovir Disoproxil Fumarate without medical supervision, or misuse the drug—such as overdosing or stopping the medication abruptly—drug resistance in the body may develop.

Therefore, patients must take Bictegravir Emtricitabine Tenofovir Disoproxil Fumarate exactly as prescribed. During treatment, they should maintain a light diet and avoid smoking and alcohol consumption to prevent interference with drug efficacy or worsening of the condition.