Elevated LDH and HBDH
LDH usually refers to lactate dehydrogenase, and HBDH usually refers to alpha-hydroxybutyrate dehydrogenase. The following explanations will use these abbreviations. Generally, elevated levels of LDH and HBDH may be caused by conditions such as viral myocarditis, coronary atherosclerotic heart disease, hypertensive heart disease, acute myocardial infarction, or renal failure. These can be improved through general treatments, medication, and other methods. Specific analyses are as follows:
1. Viral Myocarditis: This is usually caused by a viral infection affecting the heart muscle and may present symptoms such as palpitations, shortness of breath, and chest pain. When the heart muscle is damaged, levels of LDH and HBDH rise accordingly. Patients may be treated under medical guidance with medications such as mannitol injection or acyclovir glucose injection.
2. Coronary Atherosclerotic Heart Disease: This condition is often related to narrowing or blockage of the coronary arteries and can cause symptoms like chest pain and tightness. Myocardial ischemia or even necrosis resulting from the disease leads to elevated LDH and HBDH levels. Patients may be treated under medical supervision with medications such as simvastatin dispersible tablets or atorvastatin calcium tablets.
3. Hypertensive Heart Disease: This is generally caused by structural changes in the heart due to high blood pressure and commonly causes symptoms such as shortness of breath and fatigue, which may lead to the aforementioned test results. Patients may be treated under medical guidance with medications such as isosorbide nitrate tablets or captopril sustained-release tablets.
4. Acute Myocardial Infarction: This may be triggered by factors such as abnormal blood sugar levels or smoking, and commonly causes symptoms including chest discomfort, palpitations, rapid breathing, and restlessness. During examination, the aforementioned enzyme levels are typically elevated. Patients may be treated under medical supervision with medications such as ramipril tablets or enteric-coated aspirin tablets.
5. Renal Failure: Patients with renal failure often experience ongoing damage and necrosis of kidney tissue. When kidney tissue is damaged, intracellular LDH and HBDH are released into the circulatory system, leading to increased blood concentrations. Patients may be treated under medical guidance with medications such as bumetanide tablets or furosemide tablets.
In daily life, attention should be paid to cardiac health, appropriate aerobic exercise should be performed, and a positive mindset should be maintained.