When is the best time to take vardenafil for optimal effect?

Under normal circumstances, vardenafil is generally taken orally about one hour before sexual activity. The detailed explanation is as follows:

Vardenafil is a phosphodiesterase type 5 (PDE5) inhibitor and is clinically used for the treatment of erectile dysfunction. The drug requires sexual stimulation to become effective; therefore, it is typically taken prior to sexual intercourse. Note that vardenafil must not be taken with nitrates or guanylate cyclase stimulators, as this may enhance the hypotensive effects of these agents, potentially leading to persistent hypotension and symptoms such as headache, dizziness, facial flushing, and rhinitis.

In summary, patients are advised to use this medication under the guidance of a physician to avoid adverse outcomes. If any discomfort occurs during treatment, patients should seek medical attention promptly for proper diagnosis and symptomatic management.