What would be the result of taking Huoxiang Zhengqi Water together with cephalosporin?

Cephalosporins usually refer to cephalosporin antibiotics. Taking Huoxiang Zhengqi Water together with cephalosporin antibiotics may lead to disulfiram-like reactions, allergic reactions, gastrointestinal discomfort, increased liver burden, and enhanced drug toxicity.

1. Disulfiram-like reaction

Huoxiang Zhengqi Water contains alcohol. When taken concurrently with cephalosporin antibiotics, it may interact with the methythiotetrazole group in cephalosporins and trigger a disulfiram-like reaction, causing symptoms such as facial flushing, dizziness, and headache. Severe cases may involve difficulty breathing and even life-threatening complications.

2. Allergic reaction

If a patient is allergic to components in either medication, an allergic reaction may occur, manifesting as skin itching, rashes, or swelling.

3. Gastrointestinal discomfort

The combination may irritate the gastrointestinal mucosa and increase the digestive tract's workload, leading to gastrointestinal symptoms such as abdominal pain, vomiting, and nausea.

4. Increased liver burden

Both drugs are metabolized through the liver after administration. Concurrent use may overload the liver, slow down drug metabolism, cause drug accumulation in the body, and potentially damage liver function.

5. Increased drug toxicity

Taking these two medications together without medical advice may enhance drug toxicity, potentially damaging the kidneys and, in severe cases, causing shock.

If Huoxiang Zhengqi Water has already been taken with cephalosporin antibiotics, closely monitor for any symptom changes. Seek immediate medical attention if discomfort occurs, and follow a healthcare provider's guidance for appropriate management. During treatment with cephalosporin antibiotics, avoid consuming any beverages containing ethanol.