Why should nitrate medications not be used in inferior wall myocardial infarction?
An inferior wall myocardial infarction generally indicates right ventricular myocardial infarction. Nitrate medications are usually contraindicated in such cases, as they may lower blood pressure and exacerbate shock.
Nitrate medications include nitroglycerin tablets, pentaerythritol tetranitrate tablets, and isosorbide mononitrate tablets. Under normal circumstances, nitrates have vasodilatory and anticoagulant effects, helping to dilate veins and coronary arteries, relieve coronary artery spasm, and mildly dilate small arteries. Therefore, when an inferior wall myocardial infarction is complicated by right ventricular infarction, the use of nitrates can further reduce blood pressure and worsen shock.
Inferior wall myocardial infarction refers to infarction located in the inferior wall of the right ventricle and the posterior half of the interventricular septum. Patients typically experience sudden, crushing chest pain following the infarction; a minority may present with pain in the neck, jaw, or throat. Treatment primarily focuses on antiplatelet therapy and plaque stabilization, with medications such as compound aspirin tablets, clopidogrel hydrogen sulfate tablets, and atorvastatin calcium tablets used as directed by a physician.
Patients are advised to rest adequately, avoid colds and infections, quit smoking and alcohol consumption, minimize late-night activities, maintain regular sleep patterns, and follow a light diet.