Can you undergo knee replacement surgery after having received ozone therapy?

In general, knee replacement surgery can help relieve knee pain, improve knee joint function, correct knee deformities, and achieve long-term stability. In real-life situations, whether a person who has received ozone injections can undergo knee replacement surgery depends on individual circumstances—it may be possible in some cases, but not in others. The details are as follows:

1. Possible

Ozone has anti-inflammatory and antibacterial properties. Injecting ozone into the knee joint can reduce knee inflammation and help treat conditions such as knee swelling. Moreover, medical ozone is one of the commonly used agents in knee replacement surgery. Injecting medical ozone at a concentration of 40μg/ml (10–20ml per session) into the joint cavity can significantly improve joint mobility, suppress synovial inflammation, and reduce degeneration of articular cartilage. If ozone is used properly and the patient does not experience adverse reactions, it generally does not affect the normal course of knee replacement surgery.

2. Not recommended

During medical ozone therapy, the ozone concentration should not exceed 80μg/ml. Excessively high ozone concentrations may cause hemolysis and harm the patient’s body, which could make knee replacement surgery inadvisable. Therefore, patients must use ozone under the guidance of a physician and undergo appropriate physical examinations before treatment.

Patients are advised to seek timely medical attention when experiencing discomfort and to receive standardized treatment under professional medical supervision, which helps promote recovery.