What causes elevated lactate dehydrogenase and decreased prealbumin?

Sep 26, 2023 Source: Cainiu Health
Dr. Yang Shuwen
Introduction
In general, elevated lactate dehydrogenase (LDH) and decreased prealbumin levels may be related to factors such as improper diet, hemolytic anemia, hepatitis, lung abscess, and myocarditis. Patients are advised to follow medical instructions for symptomatic treatment. Additionally, these abnormalities may also be associated with conditions such as pulmonary infarction and acute lymphoblastic leukemia. If patients experience any discomfort or symptoms, they should seek timely medical attention at a hospital to avoid delays in diagnosis and treatment.

In general, elevated lactate dehydrogenase (LDH) levels and low prealbumin levels may be related to factors such as improper diet, hemolytic anemia, hepatitis, lung abscess, myocarditis, etc. Patients are advised to follow medical guidance for symptomatic treatment. Specific analyses are as follows:

1. Improper Diet

If a patient has long-term poor dietary habits, it may lead to insufficient intake of essential nutrients, potentially causing increased lactate production in the blood, resulting in elevated LDH levels and low prealbumin levels. It is important to promptly adjust eating habits and consume nutrient-rich foods such as eggs, milk, etc.

2. Hemolytic Anemia

Hemolytic anemia mainly occurs when red blood cell destruction exceeds the compensatory capacity of bone marrow hematopoiesis. Common symptoms include headache, high fever, vomiting, and muscle pain. Laboratory tests may reveal the aforementioned abnormalities. Patients are advised to take medications such as cyclosporine soft capsules or azathioprine tablets under medical supervision.

3. Hepatitis

Hepatitis may result from bacterial, viral, or parasitic infections. Symptoms include loss of appetite, fatigue, skin itching, and lethargy. Inflammation can damage liver tissue; when hepatocytes are injured, dehydrogenase enzymes are released into the bloodstream, leading to the observed changes. Patients may take liver-protective medications such as Compound Biejia Ruangan Tablets or silibinin meglumine tablets as directed by a physician.

4. Lung Abscess

A lung abscess is an infectious disease in which pathogenic microorganisms damage lung tissue, potentially causing the aforementioned laboratory abnormalities. Common symptoms include chills, cough, sputum production, and high fever. Treatment may include antibiotics such as clindamycin hydrochloride capsules or metronidazole tablets, as prescribed by a doctor.

5. Myocarditis

Myocarditis is primarily caused by viral infection of the heart muscle. Typical symptoms include chest pain, palpitations, shortness of breath, and fainting. Since myocardial cells are rich in lactate dehydrogenase, cardiac injury leads to enzyme release and the observed elevation in LDH. Antiviral medications such as acyclovir tablets or valacyclovir hydrochloride dispersible tablets may be used under medical guidance.

In addition, these findings may also be associated with conditions such as pulmonary infarction or acute lymphoblastic leukemia. If patients experience any discomfort, they should seek timely medical evaluation at a hospital to avoid delays in diagnosis and treatment.