Can Benzylic Quinuclidinium Bromide be used long-term?

Under normal circumstances, quinuclidinyl benzilate refers to quinuclidinyl benzilate nasal spray, which should not be used for prolonged periods. The specific analysis is as follows:

Quinuclidinyl benzilate nasal spray works by inhibiting cholinergic nerve-mediated glandular secretion and inflammatory responses, thereby rapidly stopping rhinorrhea. The drug primarily enters the body through the nasal cavity and may adversely affect the eye's lens and vitreous body, potentially obstructing ocular peripheral blood circulation and causing blurred vision. Long-term use may also suppress intestinal smooth muscle function, leading to reduced gastrointestinal motility and adverse reactions such as constipation and indigestion. Therefore, prolonged use is not recommended.

Patients are advised to follow medical instructions when using this medication. Before administration, the nasal cavity should be cleaned, and the spray should be used correctly according to the instructions. After spraying, patients should avoid immediately exhaling forcefully through the nostrils; exhalation should be gentle to prevent the medication from leaking out of the nasal cavity. If any discomfort occurs during treatment, patients should promptly seek medical attention at a hospital.