Coughing persistently at night after the second positive test

　　"Second infection" generally refers to a second infection with the novel coronavirus. Persistent coughing at night after a second COVID-19 infection may typically be caused by factors such as poor physical condition, allergic asthma, bronchitis, upper respiratory tract infection, or chronic laryngitis. Patients are advised to follow medical guidance for symptomatic treatment. Specific analyses are as follows:

　　1. Poor Physical Condition

　　If a patient has relatively low immunity, the body may become weaker at night and more susceptible to bacterial invasion, leading to symptoms such as coughing and fatigue. Medications such as Lianhua Qingwen Capsules or Cefixime Tablets may be taken orally as directed by a physician.

　　2. Allergic Asthma

　　At night, allergic asthma may trigger persistent coughing due to inhalation of indoor allergens such as dust mites or dust particles. Treatment should include medications like Budesonide Nasal Spray or Montelukast Sodium Chewable Tablets, as prescribed by a doctor.

　　3. Bronchitis

　　Bronchitis may cause symptoms including coughing, sputum production, and wheezing, which could lead to continuous nighttime coughing. Treatment should follow medical advice using medications such as Ambroxol Hydrochloride Dispersible Tablets or Compound Dextromethorphan Hydrobromide Syrup.

　　4. Upper Respiratory Tract Infection

　　If a patient fails to stay warm during sleep, cold exposure may lead to an upper respiratory tract infection, causing symptoms such as coughing and runny nose. Under a doctor's guidance, patients may use medications such as Amoxicillin Capsules or Compound Pseudoephedrine Hydrochloride Sustained-Release Capsules.

　　5. Chronic Laryngitis

　　Inflammatory secretions entering the larynx can directly irritate the mucous membrane, causing chronic inflammation. At night, patients may experience persistent coughing, dryness, itching, and a burning pain in the throat. Medications such as Lanqin Oral Liquid or Shuanghuanglian Oral Liquid may be used as directed by a physician.

　　Additionally, pneumonia could also be a possible cause. If patients experience discomfort, they should seek timely medical evaluation and receive targeted treatment to avoid delaying recovery.