Why does taking nirmatrelvir tablets cause severe bitterness in the mouth, and what should be done about it?

Sep 27, 2023 Source: Cainiu Health
Dr. Li Jingli
Introduction
Under normal circumstances, severe bitterness after taking nirmatrelvir tablets may be caused by differences in taste sensitivity, dietary factors, excessive drug dosage, slow drug absorption, stomach heat, or other reasons. Specific details are as follows: In summary, if symptoms persistently worsen after taking the medication, it is recommended to seek timely medical attention at a hospital to identify the underlying cause and receive appropriate treatment, so as to prevent disease progression.

Under normal circumstances, a severe bitter taste after taking nirmatrelvir tablets may be caused by differences in taste sensitivity, dietary factors, excessive drug dosage, slow drug absorption, or stomach heat. The specific details are as follows:

1. Differences in Taste Sensitivity

Different individuals have varying taste perception abilities and sensitivities, so the degree of bitterness experienced can vary from person to person. Some people may be more sensitive to bitterness, while others may perceive it less intensely. This situation is generally normal and does not require special treatment.

2. Dietary Factors

If bitter-tasting foods are consumed during medication, they may irritate the mouth and lead to a bitter sensation. Patients can rinse their mouth with plain water and suck on candy to help relieve the discomfort.

3. Excessive Drug Dosage

A high dose of medication may intensify the bitter taste. If a higher dose of nirmatrelvir tablets is taken, the bitterness may become more pronounced. Patients are advised to follow medical instructions strictly and avoid increasing the dosage without guidance.

4. Slow Drug Absorption

Individual differences in drug absorption and metabolism may also affect the occurrence and intensity of bitterness. Variations in how quickly different people absorb and metabolize the drug may influence how long it remains in the oral cavity. Patients are advised to drink an appropriate amount of water and maintain good oral hygiene.

5. Stomach Heat

If patients consume excessive amounts of spicy or heat-inducing foods after taking the medication, symptoms such as bloating, abdominal pain, and bad breath may occur. It is recommended to avoid spicy and irritating foods. Medications such as Huanglian Shangqing Tablets or Lactobacillin Tablets may be used under medical guidance for treatment.

In summary, if symptoms worsen or persist after taking the medication, patients should seek timely medical evaluation to identify the underlying cause and receive appropriate treatment, preventing potential disease progression.