A white mass was discharged after test-tube embryo transfer.

Generally, the discharge of a white mass after test-tube embryo transfer may be caused by normal vaginal secretions, residual medication, hormonal changes in the body, luteal support therapy, or vulvovaginal candidiasis. Patients are advised to follow medical instructions for symptomatic treatment. Specific analysis is as follows:

1. Normal Vaginal Secretions

In daily life, there is normally some vaginal discharge, usually in small amounts. During in vitro fertilization (IVF) treatment, medications may stimulate the body and lead to increased vaginal discharge, resulting in the expulsion of white secretions during urination. If the only symptom is increased discharge without odor, local itching, or other discomforts, it is generally considered a normal phenomenon.

2. Medication Residue

After embryo transfer, due to insufficient progesterone production, patients may need to use vaginal progesterone suppositories under medical guidance. These suppositories are milky white to light yellow in color. When the medication is not fully absorbed, part of it may be expelled from the vagina as white discharge, especially during squatting or standing movements. There is no need for excessive concern; however, repeated squatting should be minimized during treatment.

3. Hormonal Changes in the Body

Following a successful embryo transfer, estrogen levels in women rise. Continuous stimulation by estrogen can increase the amount of vaginal discharge, which is a normal physiological response. It is recommended to clean the genital area daily with warm water and wear breathable, comfortable underwear.

4. Manifestation of Luteal Support Therapy

After embryo transfer, high doses of progesterone support are required, and sometimes additional estrogen is used to enhance luteal function. Under the influence of high estrogen levels, transparent or whitish vaginal discharge may occur. Maintaining good local hygiene and frequently changing underwear are recommended.

5. Vulvovaginal Candidiasis

This condition is primarily caused by inflammation disrupting the vaginal microenvironment, leading to overgrowth of pathogenic fungi, congestion, and edema of the vaginal mucosa, resulting in increased vaginal discharge. Mild vulvovaginal candidiasis often presents with white, clumpy, or transparent discharge. Patients may initially observe symptoms; however, if symptoms become severe, antifungal treatments such as clotrimazole suppositories or econazole nitrate suppositories can be used under medical supervision.

In addition, the discharge of a white substance after embryo transfer could also be due to bacterial vaginosis. If patients experience discomfort, they should seek timely medical evaluation and receive targeted treatment to avoid disease progression.