How long after taking rifampicin do side effects appear?
Oct 10, 2023
Source: Cainiu Health
Dr. Yang Shuwen
Introduction
In general, side effects of rifampicin may appear after about 3 days of taking the medication. If a patient experiences adverse reactions after taking rifampicin, it is recommended to maintain a light diet, eat small meals frequently, and avoid spicy or irritating foods in daily life to help alleviate gastrointestinal discomfort. In severe cases, prompt medical attention is advised, and treatment should be carried out under the guidance of a physician.
Rifampicin is commonly available in tablet and capsule formulations. In general, side effects of rifampicin may appear after about 3 days of use. Specific details are as follows:
Rifampicin is a semi-synthetic bactericidal agent used in anti-tuberculosis therapy. It primarily works by inhibiting RNA transcription in bacteria, thereby exerting its bactericidal effect. It is effective not only against Mycobacterium tuberculosis but also against other mycobacterial species. During rifampicin treatment, patients frequently experience adverse reactions, most commonly gastrointestinal symptoms such as loss of appetite, nausea, vomiting, upper abdominal discomfort, and diarrhea. These symptoms are generally tolerable. Within two weeks of starting treatment, a small number of patients may develop elevated liver transaminases, hepatomegaly, or jaundice.
If a patient experiences adverse reactions after taking rifampicin, it is recommended to maintain a light diet, eat smaller meals more frequently, and avoid spicy or irritating foods to help alleviate gastrointestinal discomfort. In severe cases, prompt medical attention is advised, and treatment should be conducted under the guidance of a physician.
