Is sacubitril/valsartan a long-acting antihypertensive drug?

Oct 17, 2023 Source: Cainiu Health
Dr. Tian Hongbo
Introduction
Under normal circumstances, sacubitril/valsartan refers to sacubitril and valsartan sodium tablets, which are long-acting antihypertensive drugs. Sacubitril and valsartan sodium tablets are a combination of sacubitril and valsartan, belonging to the class of long-acting antihypertensive medications. Long-acting antihypertensive drugs refer to medications with prolonged effects that can provide stable blood pressure control for 24 hours after a single dose.

Under normal circumstances, sacubitril valsartan refers to sacubitril valsartan sodium tablets, which are a long-acting antihypertensive medication. The detailed analysis is as follows:

Sacubitril valsartan sodium tablets are a combination of sacubitril and valsartan and belong to the class of long-acting antihypertensive drugs. Long-acting antihypertensives refer to medications that maintain their effect for an extended period, capable of providing stable blood pressure control for 24 hours after a single dose. Sacubitril valsartan sodium tablets can increase enkephalin levels and block the type 1 receptor of angiotensin II, thereby exerting cardiovascular and renal effects. Therefore, sacubitril valsartan sodium tablets are considered a long-acting antihypertensive agent that helps maintain stable blood pressure.

Patients should use this medication under the guidance of a physician and must not take it casually. Concurrent use of sacubitril valsartan sodium tablets with angiotensin-converting enzyme (ACE) inhibitors may increase the risk of angioedema, so they generally should not be taken together. Additionally, patients who are allergic to any active ingredient or excipient in sacubitril valsartan sodium tablets must not use this medication. During treatment, patients should also maintain a reasonable diet and avoid spicy and irritating foods such as hot pot and chili peppers, which might interfere with the drug's effectiveness.

In daily life, it is important to develop healthy habits, avoid excessive fatigue, and refrain from strenuous exercise to prevent physical discomfort. It is recommended to engage in appropriate activities such as walking or jogging according to individual conditions, which can help enhance physical immunity and support recovery.