Are hypopigmented patches and vitiligo the same condition?

Oct 17, 2023 Source: Cainiu Health
Dr. Liu Wenmin
Introduction
In general, hypopigmented macules and vitiligo are not the same condition. The differences between hypopigmented macules and vitiligo lie in their causes, color appearance, distribution patterns, degree of pigment loss, and treatment methods. If a patient develops any discomfort or symptoms, it is recommended to seek timely medical evaluation at a hospital to avoid delaying proper diagnosis and treatment.

In general, hypopigmented macules and vitiligo are not the same condition. Differences between hypopigmented macules and vitiligo include distinct causes, color appearance, distribution patterns, degree of pigment loss, and treatment methods. Specific analyses are as follows:

1. Different causes

Hypopigmented macules may result from inadequate skin cleansing or bacterial infection, or could be caused by vitiligo; vitiligo is primarily caused by decreased immune function leading to abnormal skin pigment metabolism.

2. Different colors

The color of hypopigmented macules is lighter than normal skin tone but does not turn porcelain white; in contrast, the color of vitiligo lesions is typically milky white.

3. Different distribution patterns

Hypopigmented macules can appear on various parts of the body without specific limitations; vitiligo lesions are more commonly found on the face, hands, wrists, feet, and genital areas.

4. Different degrees of pigment loss

Hypopigmented macules occur when melanocytes in the skin are damaged or reduced, resulting in localized or widespread areas of decreased pigmentation; vitiligo, however, involves complete disappearance of melanocytes on the skin surface, forming completely white patches.

5. Different treatments

Hypopigmented macules generally lack effective treatments, whereas vitiligo can be treated with medications specifically for vitiligo and melanocyte transplantation techniques.

If patients experience any discomfort or symptoms, it is recommended to seek timely medical evaluation at a hospital to avoid delays in diagnosis and treatment.