Which age group is the quadrivalent HPV vaccine suitable for?

Oct 20, 2023 Source: Cainiu Health

Dr. Zhao Xiaodong

Introduction

Quadrivalent refers to the quadrivalent HPV vaccine, which is suitable for individuals aged 20 to 45. The quadrivalent HPV vaccine is recommended for women between 20 and 45 years of age. Those within this age range who have no contraindications can receive the quadrivalent HPV vaccine. If any adverse symptoms occur, it is advisable to seek medical attention at a hospital promptly to avoid delaying treatment.

Generally speaking, "quadrivalent" refers to the quadrivalent HPV vaccine, which is suitable for individuals aged 20 to 45. The specific analysis is as follows:

The recommended age range for the quadrivalent HPV vaccine is women aged 20 to 45. Individuals within this age group who have no contraindications can receive the quadrivalent HPV vaccine. Currently, HPV vaccines available in China include the bivalent HPV vaccine (for ages 9–45), the quadrivalent HPV vaccine (for ages 20–45), and the nonavalent HPV vaccine (for ages 9–45). Selection can be made according to age and individual needs under the guidance of a healthcare professional. Vaccination with the quadrivalent HPV vaccine is contraindicated for those with known allergies to the vaccine. Pregnant women or those planning pregnancy should delay vaccination until after completion of pregnancy.

If any adverse symptoms occur, it is recommended to seek timely medical attention at a hospital to avoid delays in diagnosis and treatment.

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Can you receive the quadrivalent HPV vaccine if infected with HPV type 58?

In general, after infection with human papillomavirus (HPV) type 58, individuals who are not allergic to vaccine components, have no underlying health conditions, and fall within the recommended age range can still receive the quadrivalent vaccine to prevent infection from other HPV types. However, vaccination is not recommended for those with persistent infections showing increased risk of cancerous changes or those allergic to vaccine components, to avoid potential adverse reactions.

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How long after receiving the quadrivalent vaccine can one get pregnant?

In general, the term "quadrivalent" refers to the quadrivalent HPV vaccine. Pregnancy can be considered six months after receiving the quadrivalent HPV vaccine. The quadrivalent HPV vaccine primarily prevents infection from HPV types 6, 11, 16, and 18. It is recommended to wait six months after completing the vaccine series before attempting pregnancy, as this allows vaccine-related adverse reactions to diminish and reduces potential risks to the fetus.

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Do I still need to check antibody levels after receiving the quadrivalent vaccine?

In general, "quadrivalent" refers to the quadrivalent HPV vaccine, and whether antibody testing is needed depends on the specific situation. If patients are concerned, antibody testing is usually recommended; if they are not concerned, antibody testing may not be necessary. Patients who are worried can undergo antibody testing for the quadrivalent HPV vaccine, as issues such as expiration of the quadrivalent HPV vaccine or incomplete administration of the full vaccine series may occur.

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How many doses of the quadrivalent HPV vaccine are required?

For individuals aged 9–14 years receiving the quadrivalent HPV vaccine for the first time and who have no contraindications to vaccination, a 2-dose schedule at 0 and 6–12 months is recommended. This age group typically exhibits a strong immune response, and two doses are sufficient to achieve optimal protective efficacy. This approach not only reduces the number of injections but also minimizes inconvenience associated with multiple visits, aligning with vaccination guidelines in most countries and regions.

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What tests are needed before receiving the quadrivalent HPV vaccine?

Examinations generally required before receiving the quadrivalent HPV vaccine may include HPV virus testing, cervical cytology examination, routine blood test, coagulation function test, and screening for infectious diseases. These tests help determine whether there is an existing HPV infection, particularly the high-risk types (types 16 and 18) and low-risk types (types 6 and 11) covered by the quadrivalent vaccine, thereby clarifying the individual's infection status prior to vaccination.

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Can I still receive the 9-valent vaccine after having received the 4-valent vaccine?

"Quadrivalent" refers to the quadrivalent HPV vaccine, and "nonavalent" refers to the nonavalent HPV vaccine. It is possible to receive the nonavalent HPV vaccine after having received the quadrivalent HPV vaccine, but certain conditions must be met, and it is not mandatory. Neither the quadrivalent nor the nonavalent HPV vaccine can guarantee 100% protection against HPV. Even after receiving the HPV vaccine, regular cervical cancer screening should still be performed.

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Is it possible to receive the third dose of the cervical cancer vaccine after the age of 45?

If the recipient was under the recommended upper age limit when receiving the first two doses of the cervical cancer vaccine—45 years for the bivalent vaccine, 45 years for the quadrivalent vaccine, and 26 years for the nonavalent vaccine—and has completed the first two doses according to the prescribed vaccination schedule, then even if the recipient's age exceeds 45 years when receiving the third dose, vaccination can still proceed.

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Is it necessary to get the HPV bivalent vaccine?

In general, whether it is necessary to receive the bivalent human papillomavirus (HPV) vaccine should be determined based on an individual's age and vaccination history. It is typically necessary for individuals aged 9–25 who have not previously received any other HPV vaccine. However, for those who have already received the quadrivalent or nonavalent HPV vaccine and are older than 25 years, vaccination with the bivalent HPV vaccine is not necessary.

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