Can a non-contrast CT scan rule out pancreatic cancer?

In general, if a non-contrast CT scan shows normal results, pancreatic cancer can usually be ruled out; however, if the results are abnormal, pancreatic cancer cannot be completely excluded. The detailed analysis is as follows:

1. Yes

When performing a non-contrast CT scan, if the pancreas appears normal, conditions such as pancreatitis and advanced pancreatic cancer can essentially be ruled out. In acute pancreatitis, non-contrast CT typically reveals obvious peripancreatic exudates, unclear pancreatic contours, or signs of edema and enlargement. Combined with clinical symptoms and serological tests, the diagnosis can be further confirmed.

2. No

However, a non-contrast CT scan of the pancreas cannot completely exclude pancreatic diseases. To fully rule out pancreatic disorders, ultrasound examination is required. The pancreas is located in the upper abdomen and plays an important role in neutralizing gastric acid and digesting proteins and fats. If a non-contrast CT scan shows localized enlargement of the pancreas, combined with patient symptoms and serological markers, this often suggests a space-occupying lesion in the pancreas, but pancreatic cancer cannot be entirely excluded.

Patients are advised to maintain a healthy lifestyle, including eating a light diet, avoiding smoking and alcohol, maintaining regular作息 (daily routines), and actively participating in physical exercise, which may help prevent pancreatic diseases.