Can getting the HPV 9-valent vaccine cause polycystic ovary syndrome (PCOS)?

Generally speaking, "nonavalent" refers to the nonavalent HPV vaccine, and "PCOS" refers to polycystic ovary syndrome. Whether receiving the nonavalent HPV vaccine can lead to polycystic ovary syndrome depends on specific circumstances. Under normal conditions, the nonavalent HPV vaccine does not cause polycystic ovary syndrome; however, if a patient has a family history of polycystic ovary syndrome, they may still develop the condition. Detailed analysis is as follows:

1. No

The nonavalent HPV vaccine is primarily used to prevent cervical cancer caused by human papillomavirus (HPV) infection. Polycystic ovary syndrome (PCOS), in contrast, is a common complex disorder in women of reproductive age resulting from endocrine and metabolic abnormalities. It is characterized by chronic anovulation and hyperandrogenism. The etiology of PCOS is unrelated to HPV infection. Therefore, receiving the nonavalent HPV vaccine usually does not lead to polycystic ovary syndrome.

2. Yes

It should be noted that the development of polycystic ovary syndrome is associated with genetic and environmental factors. For example, individuals with a family history of the condition may have an increased risk. Such patients may develop PCOS even after receiving the nonavalent HPV vaccine. Additionally, irregular lifestyle habits, unhealthy diet, and lack of physical activity may contribute to hormonal imbalances, thereby triggering polycystic ovary syndrome. Therefore, it is still possible for individuals to develop PCOS after receiving the nonavalent HPV vaccine.

If a patient experiences any discomfort or symptoms, it is recommended to seek timely medical evaluation at a hospital to avoid delays in diagnosis and treatment.