What are the common clinical diseases caused by abnormal B cell function?

B cells refer to B lymphocytes. In general, abnormal B lymphocyte function may lead to various common clinical conditions such as allergic rhinitis, chronic enteritis, rheumatoid arthritis, aplastic anemia, and systemic lupus erythematosus. If any discomfort occurs, it is recommended to seek medical treatment immediately. Specific analyses are as follows:

1. Allergic Rhinitis

Abnormal B lymphocytes may cause the immune system to overreact to allergens such as pollen or house dust mites, leading to allergic rhinitis. The development of allergic rhinitis involves excessive production of immunoglobulin antibodies by the immune system, triggering inflammatory responses. Typical symptoms include nasal congestion, runny nose, sneezing, nasal itching, and clear nasal discharge. Severe cases may result in sleep disturbances, fatigue, and difficulty concentrating. Treatment under medical guidance may include vitamin C tablets, fluticasone propionate nasal spray, and cetirizine hydrochloride oral solution.

2. Chronic Enteritis

Abnormal B lymphocytes may lead to aberrant activation of the intestinal immune system, resulting in chronic enteritis. Typical symptoms include abdominal pain, diarrhea, and weight loss. Patients may experience periodic flare-ups and remissions. Treatment under medical supervision may include acyclovir capsules, oseltamivir phosphate capsules, and minocycline hydrochloride capsules.

3. Rheumatoid Arthritis

Rheumatoid arthritis is an inflammatory condition. Abnormal B lymphocytes may trigger autoimmune attacks on joint tissues, leading to the onset of rheumatoid arthritis. Main symptoms include joint swelling, pain, and morning stiffness, along with possible fatigue, fever, and general malaise. Treatment under medical guidance may include Qingpeng ointment, diclofenac sodium sustained-release tablets, and methylprednisolone tablets.

4. Aplastic Anemia

Abnormal B lymphocytes may cause the immune system to attack hematopoietic stem cells, resulting in aplastic anemia—a rare disorder characterized by the bone marrow's inability to produce sufficient red blood cells, white blood cells, and platelets. This may lead to symptoms such as fatigue, weakness, and dizziness, as well as increased risks of infection and bleeding. The skin may appear pale due to anemia. Treatment based on physician recommendations may include deferasirox dispersible tablets, aminocaproic acid injection, and cyclosporine soft capsules.

5. Systemic Lupus Erythematosus

Abnormal B lymphocytes may also contribute to systemic lupus erythematosus, typically because dysfunctional B cells cause the immune system to attack the body’s own tissues—including the skin, joints, and kidneys—leading to the disease. Symptoms vary widely and may include joint pain, rashes, fatigue, fever, and kidney damage. The condition is characterized by periods of remission and acute flares. Treatment under medical guidance may include hydroxychloroquine sulfate tablets, azathioprine tablets, and prednisone acetate tablets.

In daily life, maintaining a light diet, regular作息 (sleep schedule), and adequate hydration can help support overall health.