Can nitroglycerin be used for variant angina?

Nitroglycerin is commonly available in various formulations such as ointments, aerosols, injections, and tablets. Nitroglycerin is generally used to treat variant angina; however, it is important to follow medical advice when taking this medication. If any discomfort occurs, prompt medical attention is recommended.

Nitroglycerin is a vasodilating agent whose primary mechanism of action involves directly relaxing vascular smooth muscle, thereby dilating blood vessels, reducing peripheral resistance and myocardial oxygen consumption, and promoting coronary collateral circulation, which helps relieve symptoms of angina pectoris. Variant angina is a special type of angina characterized by episodes unrelated to physical exertion; its underlying mechanism is associated with coronary artery spasm. Therefore, nitroglycerin can be used in the treatment of variant angina. However, it should be noted that while nitroglycerin is effective for treating variant angina, its long-term efficacy remains uncertain.

Patients should use nitroglycerin under the guidance of a physician and take medications appropriately. During treatment, it is advisable to actively manage risk factors for cardiovascular disease, such as hypertension, hyperglycemia, and hyperlipidemia, and maintain healthy lifestyle habits, including quitting smoking, limiting alcohol intake, and maintaining a balanced diet.

In daily life, individuals should cultivate good living habits, ensure sufficient sleep, avoid staying up late, and maintain a positive mood, avoiding negative emotions such as anxiety and irritability, all of which contribute to overall health.