What causes high urine creatinine?

Elevated urine creatinine levels may be caused by factors such as intense physical exercise, high-protein diet, glomerulonephritis, diabetic nephropathy, and hypertensive nephropathy. It is recommended to seek medical attention promptly, identify the underlying cause, and receive symptomatic treatment under the guidance of a qualified physician. Specific analyses are as follows:

1. Intense physical exercise: This may increase the body's metabolic rate, leading to increased muscle breakdown and metabolism, thereby producing more creatinine. In such cases, elevated urine creatinine levels may be temporary and typically return to normal after adequate rest, so there is generally no need for excessive concern.

2. High-protein diet: Consuming excessive amounts of high-protein foods—such as chicken and fish—in a short period may increase the burden on the kidneys, resulting in elevated urine creatinine levels. It is recommended to adjust dietary habits, reduce intake of these high-protein foods, and maintain a balanced diet to help alleviate symptoms.

3. Glomerulonephritis: This condition may be associated with improper use of nephrotoxic medications, poor dietary habits, and other factors. After onset, increased glomerular filtration rate may lead to elevated urine creatinine levels. Symptoms may also include edema and hematuria. Patients are advised to follow medical instructions for treatment with medications such as furosemide injection, erythromycin tablets, and methylprednisolone tablets.

4. Diabetic nephropathy: This may be related to excessive protein intake, smoking, and other factors. After developing diabetes, metabolic abnormalities may occur; if blood glucose remains poorly controlled over a long period, kidney function may become impaired, leading to elevated urine creatinine levels. Additional symptoms may include polyuria (excessive urination) and thirst. Management involves actively controlling blood glucose levels and using antidiabetic medications as prescribed to improve renal function. Patients are advised to take medications such as Keloxxin capsules, irbesartan dispersible tablets, and dapagliflozin tablets as directed by their physician.

5. Hypertensive nephropathy: This is usually caused by factors such as high psychological stress and obesity. After developing hypertension, persistently high blood pressure over time can increase intraglomerular pressure, leading to glomerular fibrosis, which may impair kidney function and elevate urine creatinine levels. Other possible symptoms include headache and dizziness. Patients are advised to use medications such as nifedipine sustained-release tablets, felodipine tablets, and compound furosemide tablets under medical supervision to manage symptoms.

In daily life, patients are encouraged to follow a low-fat, low-salt diet, drink plenty of warm water, consume fresh vegetables such as bok choy, cucumber, and tomatoes in moderation, and maintain sufficient sleep, all of which are beneficial for overall health.