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What are the differences between nifedipine controlled-release tablets and nifedipine sustained-release tablets?

Jun 05, 2024 Source: Cainiu Health
Dr. Wang Xin
Introduction
The differences between nifedipine controlled-release tablets and sustained-release tablets include their release mechanisms, release rates, duration of action, therapeutic effects, and adverse reactions. These medications should be used only under a doctor's guidance; patients must not use them without authorization to avoid adverse effects. During treatment, patients should avoid eating hot pot, spicy tofu, and other spicy, raw, cold, or irritating foods, as these may affect the drug's efficacy.

Under normal circumstances, the differences between nifedipine controlled-release tablets and sustained-release tablets include release mechanism, release rate, duration of action, efficacy, and adverse reactions. These medications should be used only under a doctor's guidance; patients must not use them without authorization to avoid adverse effects. If discomfort occurs after taking the medication, prompt medical consultation is recommended for appropriate treatment under professional supervision. Specific analysis is as follows:

1. Release Mechanism

Nifedipine controlled-release tablets are manufactured using special tablet materials and laser-drilling technology to enable constant-rate drug release in the body. In contrast, nifedipine sustained-release tablets incorporate sustained-release agents into the formulation to allow gradual drug release.

2. Release Rate

Due to differences in manufacturing processes, nifedipine controlled-release tablets have a slower release rate and longer-lasting effects, whereas nifedipine sustained-release tablets release the drug more quickly and have a relatively shorter duration of action.

3. Duration of Action

The effect of nifedipine controlled-release tablets lasts longer, approximately 24 hours, while the effect of nifedipine sustained-release tablets is shorter, typically lasting about 12 hours.

4. Efficacy

Because nifedipine controlled-release tablets provide continuous and steady drug release, their therapeutic effect is relatively stable. In comparison, the efficacy of nifedipine sustained-release tablets may fluctuate.

5. Adverse Reactions

Nifedipine controlled-release tablets generally cause fewer adverse reactions, whereas nifedipine sustained-release tablets may lead to symptoms such as headache, facial flushing, and increased heart rate.

During medication treatment, patients should avoid consuming spicy, cold, or irritating foods such as hot pot, coffee, ice cream, and spicy hot dishes, as these may interfere with drug efficacy and hinder recovery.

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