What causes blisters due to sweaty palms?

Aug 31, 2024 Source: Cainiu Health
Dr. Liu Wenmin
Introduction
Palmar hyperhidrosis accompanied by blisters may be caused by various factors such as stress or anxiety, physical labor or exercise, dyshidrotic eczema, atopic dermatitis, or tinea manuum. During emotional fluctuations, increased sympathetic nervous system activity leads to excessive sweating of the palms. Excessive sweat may soften the stratum corneum, subsequently resulting in blister formation. Learning relaxation techniques—such as deep breathing, meditation, or yoga—can help reduce stress and anxiety.

Under normal circumstances, sweaty palms accompanied by blisters may be caused by various factors such as tension or anxiety, physical labor or exercise, dyshidrotic eczema (pompholyx), eczema, or tinea manuum (fungal infection of the hands). It is recommended to seek medical attention promptly, identify the underlying cause, and receive symptomatic treatment under the guidance of a qualified physician. Specific analyses are as follows:

1. Tension or Anxiety

During emotional fluctuations, increased sympathetic nervous system activity leads to excessive sweating of the palms. Excess sweat may soften the stratum corneum, potentially resulting in blister formation. Learning relaxation techniques can help reduce tension and anxiety.

2. Physical Labor or Exercise

During physical labor or exercise, the body generates significant heat, prompting sweat glands to secrete more sweat for cooling. When palms experience prolonged friction and pressure, sweat cannot evaporate quickly, making it easier for blisters to form on the skin surface. Wearing appropriate protective gloves is recommended to reduce hand friction.

3. Dyshidrotic Eczema (Pompholyx)

Dyshidrotic eczema is associated with impaired sweat gland excretion, leading to accumulation of sweat in deeper layers of the skin and subsequent blister formation. It may be accompanied by itching and a burning sensation. Symptoms can be relieved under medical supervision using medications such as compound acetic acid dexamethasone cream, cefixime tablets, or prednisone acetate tablets.

4. Eczema

Eczema is caused by factors such as allergies and immune dysfunction. Patients often have impaired skin barrier function, making them prone to allergic reactions that result in blisters on the palms. Other symptoms may include itching and erosion. It is recommended to use medications such as mizolastine sustained-release tablets, loratadine tablets, or amoxicillin capsules under the guidance of a healthcare professional.

5. Tinea Manuum (Hand Fungus)

Tinea manuum is a fungal skin infection in which fungi grow and multiply within the skin's keratin layer, causing inflammatory reactions and blister formation. Symptoms may include itching, scaling, and skin thickening. Treatment under a doctor’s supervision may include antifungal medications such as clotrimazole cream, terbinafine hydrochloride tablets, or amorolfine hydrochloride cream.

In daily life, maintain dry hands, establish regular作息 (sleep-wake) routines, and follow a light, balanced diet.

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