What is the best way to remove nasolabial folds?

In general, there is no single best method for eliminating nasolabial folds. Nasolabial folds may be caused by various factors such as genetic predisposition, skin aging, frequent facial expressions, endocrine disorders, or seborrheic dermatitis. Treatment options include general skincare, medication, hyaluronic acid injections, autologous fat grafting, and botulinum toxin injections (wrinkle-relaxing injections), all of which should be performed under the guidance of a qualified physician. Specific analyses are as follows:

1. Genetic Factors

Due to inherited skin characteristics, some individuals may naturally have thinner skin or weaker elasticity, making them more prone to developing wrinkles, including nasolabial folds. Maintaining skin hydration and using moisturizing skincare products can help. Under professional medical supervision, hyaluronic acid injection is recommended. Hyaluronic acid is a natural polysaccharide found in human tissues. When injected into the nasolabial fold area, it quickly replenishes moisture and volume beneath the skin, effectively smoothing out wrinkles and restoring a smoother appearance. The reference cost is generally between 3,000 and 8,000 yuan per session. Improvement can typically be seen within 1–2 hours after treatment, although possible side effects may include allergic reactions, infection, or bruising.

2. Skin Aging

With age, the skin gradually loses elasticity and moisture, leading to sagging and wrinkle formation. As skin support weakens, prominent nasolabial folds may develop around the sides of the nose. It's important to maintain clean skin and avoid excessive pulling during daily routines. Autologous fat grafting can be performed under the guidance of a specialist. This involves extracting fat from other parts of the patient’s body—such as the abdomen or thighs—processing it, and then injecting it into the nasolabial folds. The regenerative capacity of fat cells helps fill and repair wrinkles. The reference cost ranges from 6,000 to 30,000 yuan per session. Results usually become visible after 1–2 months, but potential risks include uneven fat absorption, infection, bruising, and nodule formation.

3. Expressive Facial Movements

Frequently making exaggerated facial expressions, especially those involving the mouth and nose, can lead to overstretching and compression of the skin in specific areas over time, eventually forming wrinkles such as nasolabial folds. Reducing the frequency of exaggerated expressions and consciously relaxing facial muscles may help. Botulinum toxin injections (commonly known as "wrinkle-relaxing injections") may also be used under medical supervision. The main component is injectable type A botulinum toxin, which blocks neurotransmitter transmission at neuromuscular junctions, causing temporary muscle relaxation and thereby reducing wrinkles. The reference price is generally between 3,000 and 8,000 yuan per injection. Results typically appear within 1–3 months, though possible side effects include localized muscle weakness and unnatural facial expressions.

4. Endocrine Disorders

Endocrine imbalances—such as abnormal thyroid function or hormonal imbalances—can impair normal skin metabolism and repair mechanisms, contributing to the development of nasolabial folds. These conditions may be accompanied by symptoms like irregular menstruation, insomnia, and mood swings. Treatment should follow medical advice and may include medications such as progesterone capsules, compound vitamin B tablets, or vitamin E softgels.

5. Seborrheic Dermatitis

Seborrheic dermatitis is a chronic inflammatory skin condition that may be associated with Malassezia yeast colonization, increased sebum production, or immune system dysfunction. This condition leads to excessive oil secretion, resulting in enlarged pores. Symptoms may include redness and scaling. Patients should use medications such as ketoconazole cream, tacrolimus ointment, or pimecrolimus cream as directed by their physician.

It is recommended to seek treatment at a reputable medical facility under the supervision of a qualified doctor to ensure both effectiveness and safety. In daily life, maintaining proper skin hydration, avoiding excessive skin stretching, and minimizing exaggerated facial expressions are beneficial. Additionally, adopting healthy lifestyle habits and maintaining regular sleep patterns can help support overall skin health.