Can HPV become negative after laser surgery?

HPV refers to human papillomavirus. Whether HPV can turn negative after laser surgery depends on the severity of infection, the patient's physical condition, and other factors. Generally, patients with stronger immunity and milder infections may achieve an HPV-negative status following laser surgery. However, if the infection is severe and the patient's constitution is weak, the virus may persist after surgery, making it difficult to achieve a negative result. The details are as follows:

Human papillomavirus can cause lesions such as genital warts or cervical condyloma acuminata. Laser surgery is primarily used to remove visible warts and does not have antiviral effects. However, if the current infection is mild, symptoms are not obvious, and the patient has good immune function, the viral load in the body may gradually decrease and eventually disappear after removal of the warts, leading to a negative HPV test result.

Conversely, if the patient has poor immunity, a severe infection, and noticeable symptoms, the virus may persist in the body even after laser removal of the warts. In such cases, achieving a negative status is unlikely. It is important to promptly begin antiviral treatment under a doctor’s guidance, such as recombinant human interferon α2b for injection, bleomycin hydrochloride for injection, or acyclovir tablets.

Even if HPV becomes negative, this does not guarantee lifelong immunity or prevent future reinfection. Therefore, regular follow-up visits to the hospital are necessary, and patients should promptly improve unhealthy lifestyle habits, including maintaining personal hygiene and practicing safe sexual hygiene.