What causes uremia?

Sep 22, 2024 Source: Cainiu Health
Dr. Yang Guang
Introduction
Chronic glomerulonephritis is caused by factors such as infections, which lead to inflammatory damage of the glomerular structure and gradual loss of filtration function, potentially resulting in uremia. It is usually accompanied by symptoms such as proteinuria, hematuria, and edema. Patients may take medications such as compound cyclophosphamide tablets, irbesartan tablets, and enalapril maleate tablets according to medical advice.

Under normal circumstances, uremia can be caused by factors such as aging, dehydration, kidney stones, chronic glomerulonephritis, and diabetic nephropathy. It is recommended to seek medical attention promptly, identify the underlying cause, and receive symptomatic treatment under the guidance of a qualified physician. The specific analysis is as follows:

1. Aging

With advancing age, the glomerular filtration rate declines and the kidney's self-repair capacity weakens, increasing the risk of developing uremia. Regular monitoring of kidney function is advised, along with maintaining controlled blood pressure and blood glucose levels, and avoiding nephrotoxic medications.

2. Dehydration

Severe dehydration may lead to inadequate renal perfusion, triggering acute kidney injury, which can progress to uremia. Prompt fluid replacement is recommended to correct electrolyte imbalances, with intravenous fluids administered when necessary.

3. Kidney Stones

Kidney stones typically form due to increased concentration or decreased solubility of stone-forming substances in urine. Recurrent kidney stones may lead to pyelonephritis and subsequent parenchymal kidney damage, ultimately resulting in uremia. Common symptoms include severe flank pain and hematuria. Patients may take medications such as Shistone Granules, Compound Lysimachia Granules, or Acetylcysteine Tablets as directed by their physician.

4. Chronic Glomerulonephritis

Chronic glomerulonephritis is often triggered by infections and other factors, causing inflammatory damage to the glomerular structure. Over time, this leads to progressive loss of filtration function and may result in uremia. It is commonly accompanied by symptoms such as proteinuria, hematuria, and edema. Treatment may include medications such as Compound Cyclophosphamide Tablets, Irbesartan Tablets, or Enalapril Maleate Tablets, taken as prescribed.

5. Diabetic Nephropathy

Diabetic nephropathy may arise from genetic predisposition, elevated glomerular filtration rate, and persistently high blood glucose levels. Hyperglycemia induces a state of glomerular hyperfiltration, leading to thickening of the glomerular basement membrane and damage to the filtration barrier, potentially progressing to uremia. It is often associated with complications such as retinopathy and neuropathy. Treatment should follow medical advice and may include medications such as Rosiglitazone Hydrochloride Tablets, Miglitol Calcium Tablets, or Metformin Hydrochloride Tablets.

In daily life, it is important to maintain adequate hydration, avoid spicy and irritating foods, and engage in regular exercise to strengthen the immune system.