What causes the vaginal opening to appear white, as if it has been blistered?

Under normal circumstances, whitening of the vaginal opening resembling a blister rupture may be caused by factors such as trauma, candidiasis, bacterial vaginosis, vulvitis, or genital warts. If abnormalities occur, timely medical consultation is recommended. Detailed analysis is as follows:

1. Trauma

If women do not pay attention to safety in daily life—for example, falling off a bicycle or having the genital area compressed by heavy objects—this may cause injury to the external genitalia, leading to whitening at the wound site, possibly accompanied by symptoms such as pain and bleeding. It is recommended to rest adequately, wear comfortable and loose clothing, and maintain a light diet.

2. Candidiasis (Yeast Infection)

Candida is a common type of fungus. When it overgrows in the vagina, it can cause itching and increased discharge that appears cheese-like or curd-like. Symptoms include whitening of the vaginal opening, itching, and a burning sensation. Treatment under a doctor’s guidance may include clotrimazole cream, ketoconazole cream, itraconazole capsules, or terbinafine hydrochloride tablets.

3. Bacterial Vaginosis

Bacterial vaginosis occurs when beneficial bacteria in the vagina—such as lactobacilli—decrease in number, allowing harmful bacteria like Gardnerella to overgrow. This leads to an elevated vaginal pH and inflammation of the vaginal mucosa, resulting in symptoms such as whitening of the vaginal opening, unpleasant odor, increased vaginal discharge with a fishy smell. Medications prescribed by a doctor, such as metronidazole tablets, clindamycin ointment, or tinidazole tablets, can help control the condition.

4. Vulvitis

Vulvitis may result from prolonged friction, urine irritation, or excessive vaginal discharge, causing inflammation of the vulva. This may lead to white patches on the vulvar area, accompanied by significant itching. Patients should keep the vulvar area clean and dry and, under medical supervision, use local treatments such as nystatin tablets, fluconazole tablets, or itraconazole capsules.

5. Genital Warts

Genital warts are caused by human papillomavirus (HPV) infection. When the virus irritates the skin around the vaginal opening, it may cause ulceration and whitening of the affected area, possibly accompanied by pain. Doctors typically recommend cryotherapy, electrocautery, laser therapy, or topical medications such as imiquimod cream, podophyllotoxin ointment, or recombinant human interferon α2b injection.

In daily life, maintaining personal hygiene, keeping the vulvar area clean and dry, and avoiding unhygienic sexual practices can help prevent gynecological diseases.