What causes vertical wrinkles between the eyebrows, and how should they be managed?
In general, vertical lines between the eyebrows are commonly known as "frown lines" or "glabellar lines." In daily life, these lines can be improved through methods such as massage, medication, lifestyle adjustments, and dietary changes. For faster improvement, treatments such as botulinum toxin type A injections, autologous fat grafting, fractional laser therapy, and radiofrequency therapy can effectively reduce frown lines.
If frown lines are caused by stress-induced frowning, relaxation techniques such as massaging the temples can help ease both mind and body, reduce stress, and relieve fatigue. Additionally, gently massaging the skin around the eyebrows with fingertips can promote blood circulation and enhance skin elasticity, thereby reducing the appearance of wrinkles. For more severe frown lines, medications such as vitamin E cream or hydroquinone cream may be used under medical guidance. Maintaining healthy lifestyle habits—such as ensuring adequate sleep, avoiding late nights, and minimizing stress—helps maintain metabolic balance, reduce sebum production, and prevent wrinkle formation. A diet rich in fresh vegetables, fruits, and foods high in protein and vitamins can help inhibit excess oil secretion and slow skin aging. It is advisable to avoid excessive consumption of fried, spicy, and irritating foods.
Illustration of frown lines:

Analysis of treatment options for improving frown lines:
Item |
Botulinum Toxin Type A Injection |
Autologous Fat Grafting |
Radiofrequency Therapy |
Fractional Laser |
Description |
Blocks neuromuscular transmission to reduce vertical lines |
Uses patient's own fat to fill lines and stimulate collagen regeneration |
Heat energy promotes fiber regeneration and reduces or fades vertical lines |
Thermal stimulation induces collagen regeneration, tightening and fading lines |
Advantages |
1. Simple procedure |
1. Convenient source material |
1. High precision |
1. High precision |
Potential Risks |
1. Muscle weakness |
1. Infection |
1. Swelling and redness |
1. Redness, swelling, and pain |
Duration of Effect |
3–13 months |
2–3 years |
2–3 years |
2–3 years |
Reference Price |
2,000–6,000 RMB per session |
5,000–20,000 RMB per session |
2,000–5,000 RMB per session |
2,000–5,000 RMB per session |
The choice of treatment method should be based on individual circumstances, medical advice, and budget considerations.