Can long-term use of arginine cause kidney failure?

Oct 30, 2024 Source: Cainiu Health
Dr. Yang Ziqi
Introduction
Arginine is an amino acid, commonly available in formulations such as arginine ibuprofen tablets, arginine hydrochloride injection, and arginine ibuprofen granules. Whether long-term use of arginine may lead to kidney failure depends on individual circumstances and requires personalized assessment. When taking arginine, it is important to follow the advice of a physician or nutritionist and adhere to the recommended dosage to avoid adverse effects from excessive intake.

Renal failure generally refers to kidney failure. Arginine is a type of amino acid, and common formulations include arginine ibuprofen tablets, arginine hydrochloride injection, and arginine ibuprofen granules. In healthy adults with normal kidney function and no chronic diseases, long-term use of arginine does not cause renal failure; however, individuals on long-term high-protein diets may face an increased risk of kidney failure with prolonged arginine supplementation. The specific analysis is as follows:

In healthy adults with normal kidney function and no chronic conditions, arginine supplementation is generally safe. Arginine is an essential amino acid in the human body that participates in various physiological processes such as protein synthesis and nitrogen metabolism. Long-term intake can help maintain overall health.

For individuals on long-term high-protein diets—especially those seeking muscle growth through exercise and fitness—additional high-dose arginine supplementation may increase the metabolic burden on the kidneys and elevate the risk of renal failure.

When taking arginine, it is important to follow the advice of a physician or nutritionist and adhere to recommended dosages to avoid adverse effects from excessive intake.

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