Why long-acting white blood cell boosters are not recommended

Under normal circumstances, long-acting white blood cell booster injections refer to long-acting granulocyte colony-stimulating factor (G-CSF) injections, which are medications used to treat leukopenia caused by chemotherapy or other factors. The use of long-acting granulocyte colony-stimulating factor injections is not recommended without medical supervision, as it may lead to adverse effects such as allergic reactions, bone pain, gastrointestinal disturbances, immune system dysregulation, and drug dependency. It is advised to seek timely medical attention, identify the underlying cause, and receive appropriate treatment under the guidance of a qualified physician. Detailed explanations are as follows:

1. Allergic Reactions

Some components in long-acting granulocyte colony-stimulating factor injections may trigger allergic reactions in patients. Therefore, an allergy test should be performed before administration to ensure patient safety. Patients should undergo allergy testing prior to receiving long-acting white blood cell booster injections to confirm whether they are allergic to any of the drug's ingredients.

2. Bone Pain

Long-acting granulocyte colony-stimulating factor stimulates bone marrow hematopoiesis, which may result in bone and muscle pain, particularly in areas such as the sternum, lower back, and muscles. Such pain can affect a patient’s daily activities and comfort level. Pain can be alleviated through rest, warm compresses, massage, and similar measures.

3. Gastrointestinal Reactions

The use of long-acting granulocyte colony-stimulating factor injections may irritate the digestive system, leading to symptoms such as loss of appetite, nausea, and vomiting, which can impair nutritional intake and overall physical condition. Patients are advised to maintain healthy eating habits, consume easily digestible foods, and avoid greasy or irritating foods. Additionally, under medical guidance, medications that protect the gastric mucosa and promote digestion may be used as adjunctive therapy.

4. Immune System Dysregulation

Long-term use of long-acting granulocyte colony-stimulating factor injections may lead to fatigue of hematopoietic cells in the bone marrow, thereby impairing normal blood cell production and potentially causing decreased white blood cell counts. It may also cause abnormal activation of bone marrow hematopoietic cells, leading to immune system dysregulation. After discontinuation, patients may experience symptoms of weakened immunity. Patients should monitor their health closely and promptly consult their doctor if signs of immunosuppression occur, so that treatment plans can be adjusted accordingly.

5. Drug Dependency

Prolonged use of long-acting granulocyte colony-stimulating factor injections may increase risks such as impaired hematopoietic function and reduced drug sensitivity. Moreover, long-term use may lead to dependency. It is recommended that patients have thorough discussions with their doctors, carefully evaluate potential risks, and strictly follow medical instructions for medication use and monitoring.

In daily life, patients should adjust their diet, increase physical activity, and ensure adequate rest to enhance the body’s natural recovery capacity.