Can Irbesartan Tablets treat kidney disease?

Generally, Irbesartan Tablets can be used as an adjunctive treatment for kidney disease, and it is recommended to use this medication under a physician's guidance. Detailed analysis is as follows:

Irbesartan Tablets are a type of angiotensin II receptor antagonist. They function by reducing intraglomerular pressure, decreasing urinary protein excretion, and protecting kidney function. Primarily, they inhibit the binding of angiotensin II to AT1 receptors, thereby suppressing vasoconstriction, reducing vascular resistance, decreasing aldosterone secretion, and exerting antihypertensive effects. Additionally, they reduce protein filtration through the glomerulus, thus alleviating kidney damage.

Irbesartan Tablets are a foundational medication for kidney disease caused by primary hypertension. By lowering blood pressure, they reduce the burden on the kidneys and protect kidney function. Irbesartan Tablets also help control blood pressure, delay the progression of kidney disease, and reduce urinary protein excretion, thus protecting the kidneys from further damage.

However, it should be noted that Irbesartan Tablets may cause a mild decline in kidney function and hyperkalemia. Therefore, patients with elevated creatinine levels or existing hyperkalemia should avoid using this medication. Patients with renal artery stenosis or a single kidney should also use it with caution. Furthermore, individuals allergic to this product, women in the second or third trimester of pregnancy, and breastfeeding women should not use this medication.