What are the long-term risks of taking glutamine?

Common dosage forms include capsules, granules, powders, etc. Generally, long-term use of glutamine may lead to side effects such as anorexia, constipation, peptic ulcer, impaired kidney function, and liver dysfunction. It is recommended to consult a professional physician before using the medication regularly. Detailed explanations are as follows:

1. Anorexia: Long-term and excessive use of glutamine may affect the digestive system, causing symptoms such as loss of appetite, nausea, and abdominal distension, which may manifest as anorexia.

2. Constipation: Glutamine may increase the absorption of sodium and chloride in the intestines, as well as enhance water absorption, potentially leading to dry stools and constipation.

3. Peptic Ulcer: Prolonged excessive use of glutamine may irritate the gastrointestinal mucosa, stimulate excessive secretion of digestive fluids, possibly leading to ulcers in the gastrointestinal mucosa, accompanied by local pain and bleeding.

4. Impaired Kidney Function: Long-term or excessive intake of glutamine may result in excessively high blood concentrations, exceeding the excretion capacity of the kidneys, increasing the burden on the kidneys, and potentially causing kidney damage.

5. Liver Dysfunction: Frequent use of high-dose glutamine may damage liver cells, increase the burden on the liver, and impair normal liver function.

It is recommended to use glutamine regularly under the guidance of a qualified physician, avoiding self-administration and increasing the dosage arbitrarily to prevent harm to the body. During treatment, maintain a regular lifestyle, avoid staying up late, and engage in moderate physical activities such as walking or practicing tai chi, which can help enhance immunity and promote recovery.