What are the functions and uses of chloramphenicol eye ointment?

Generally, the efficacy and functions of chloramphenicol eye ointment include antibacterial action, anti-infective action, anti-inflammatory action, analgesic action, and promotion of wound healing. Detailed explanations are as follows:

1. Antibacterial Action

Chloramphenicol in the eye ointment can inhibit bacterial growth and reproduction, effectively reducing the number of bacteria in the eye and preventing further deterioration of ocular infections.

2. Anti-infective Action

Chloramphenicol eye ointment interferes with bacterial protein synthesis, thereby preventing bacterial growth and proliferation to achieve anti-infective effects. It is used to treat ocular infections caused by susceptible bacteria such as Haemophilus influenzae and Klebsiella species, including conjunctivitis, keratitis, blepharitis, and trachoma.

3. Anti-inflammatory Action

By inhibiting the production and release of inflammatory mediators, chloramphenicol eye ointment can reduce tissue edema and swelling, alleviate ocular inflammatory reactions, and thus relieve discomfort in patients.

4. Analgesic Action

Chloramphenicol eye ointment can inhibit nerve conduction, providing a certain pain-relieving effect, and can alleviate mild ocular pain.

5. Promotion of Wound Healing

Certain components of chloramphenicol eye ointment help improve local blood circulation and accelerate the process of cell regeneration and tissue repair, thus promoting faster wound healing.

When using chloramphenicol eye ointment, it is important to follow medical advice to ensure appropriate medication use and avoid self-medication. Additionally, patients should maintain good ocular hygiene during treatment and avoid rubbing the eyes with hands to prevent worsening of the condition.