How is pancreatic cancer caused?

Generally, pancreatic cancer may be caused by genetic factors, smoking, chronic pancreatitis, hyperlipidemia, diabetes, and other factors. If experiencing any discomfort, it is recommended to seek medical attention promptly. Detailed explanations are as follows:

1. Genetic Factors

Mutations in the BRCA2 gene are not only associated with breast cancer but also with an increased risk of pancreatic cancer. Additionally, if multiple family members have pancreatic cancer, it may indicate a hereditary predisposition. High-risk individuals with a family history should undergo regular pancreatic imaging examinations, such as abdominal CT or MRI, for early detection of abnormalities.

2. Smoking

Smoking is one of the main risk factors for pancreatic cancer. Chemical substances in tobacco can damage DNA and promote abnormal proliferation and carcinogenesis of pancreatic epithelial cells. Quitting smoking is a key preventive measure for pancreatic cancer.

3. Chronic Pancreatitis

Chronic pancreatitis results from a combination of genetic, environmental, and other pathogenic factors. Long-term inflammatory stimulation may lead to abnormal changes in pancreatic tissue, thereby increasing the risk of pancreatic cancer, which may be accompanied by symptoms such as nausea and vomiting. Patients should follow medical advice to use medications such as octreotide acetate for injection, pantoprazole sodium enteric-coated capsules, and indomethacin tablets for treatment.

4. Hyperlipidemia

In patients with hyperlipidemia, excessive fat in the body may deposit in pancreatic tissue, increasing the burden on the pancreas and thus raising the risk of pancreatic cancer, which may manifest symptoms such as dizziness and claudication. Patients can use medications such as amlodipine atorvastatin calcium tablets, simvastatin capsules, and fenofibrate capsules under the guidance of qualified physicians for treatment.

5. Diabetes

Long-term consumption of high-sugar foods, obesity, and other factors can lead to diabetes. Due to insufficient insulin secretion or insulin resistance, diabetic patients may experience persistently elevated blood glucose levels. A hyperglycemic state may damage pancreatic tissue and promote the development of pancreatic cancer, possibly accompanied by symptoms such as polyphagia and polyuria. It is recommended to follow medical instructions to use medications such as metformin hydrochloride tablets, gliclazide modified-release tablets, and glipizide extended-release tablets for treatment.

A bland diet and appropriate physical exercise are recommended, as they can promote blood circulation, enhance physical condition, and help alleviate the condition.