Why is my menstrual flow very heavy after taking dydrogesterone tablets?

Generally, abnormally heavy menstrual bleeding after taking dydrogesterone tablets may be caused by factors such as insufficient or improper medication dosage, endocrine disorders, endometrial polyps, endometriosis, or endometrial hyperplasia. The appropriate solution depends on the specific cause to achieve effective treatment. Prompt medical consultation and treatment according to medical advice are recommended. Detailed explanations are as follows:

1. Insufficient or improper medication dosage: Dydrogesterone tablets are a type of progestogen medication used to treat various conditions caused by endogenous progesterone deficiency. If not taken correctly as directed by a physician—such as taking an insufficient dosage or missing doses—progesterone levels in the body may become unstable, thereby affecting the normal growth and shedding of the endometrium and leading to abnormally heavy menstrual bleeding. Adequate rest should be ensured, and excessive fatigue should be avoided to prevent worsening of symptoms.

2. Endocrine disorders: During treatment with dydrogesterone tablets, conditions such as excessive work-related stress, overexertion, or frequent late-night activities may lead to endocrine disorders, which can affect endometrial growth and shedding, resulting in increased menstrual bleeding. It is recommended to regulate daily routines, ensure sufficient sleep, and avoid staying up late or overexertion.

3. Endometrial polyps: This condition involves the overgrowth of localized endometrial tissue, forming a polyp that can irritate the endometrium and cause increased menstrual bleeding. During dydrogesterone therapy, the presence of polyps might further irritate the endometrium, exacerbating the symptom of heavy menstrual bleeding. Anti-inflammatory and hormone-regulating medications such as levofloxacin hydrochloride capsules, amoxicillin capsules, or progesterone capsules may be used under medical supervision.

4. Endometriosis: This condition refers to the presence of endometrial tissue outside the uterine cavity and muscular layer. During dydrogesterone therapy, the drug may affect the growth and shedding of the endometrium, causing increased bleeding from ectopic endometrial tissue and resulting in heavier menstruation. Under a physician's guidance, medications such as danazol capsules, gestrinone capsules, or norethisterone tablets may be prescribed to inhibit estrogen and progesterone activity.

5. Endometrial hyperplasia: This condition is characterized by structural changes in endometrial glands and an increased number of glands. During dydrogesterone therapy, the medication may affect the growth and shedding rate of the endometrium, leading to rapid endometrial proliferation and resulting in increased menstrual bleeding. Surgical treatments such as curettage, endometrial ablation, or hysterectomy may be considered under a physician's guidance.

Maintaining healthy lifestyle and dietary habits is important in daily life; excessive fatigue and consumption of spicy, irritating, or greasy foods should be avoided.