What is the number one best cholesterol-lowering medication?

Generally, clinically common lipid-lowering medications with better efficacy include atorvastatin calcium tablets, fenofibrate tablets, ezetimibe tablets, inositol nicotinate tablets, rosuvastatin calcium tablets, etc. The specific analysis is as follows:

1. Atorvastatin Calcium Tablets: These work by inhibiting HMG-CoA reductase, thereby reducing cholesterol synthesis and lowering plasma total cholesterol and low-density lipoprotein cholesterol levels. It is suitable for patients with mixed hyperlipidemia and coronary atherosclerotic heart disease and is a lipid-lowering drug widely used in clinical practice.

2. Fenofibrate Tablets: Fenofibrate tablets belong to the fibrate class of drugs and mainly lower blood lipids by reducing fat breakdown and inhibiting the liver's synthesis of triglycerides. It is particularly effective in treating hypertriglyceridemia and can also lower cholesterol levels, making it suitable for patients with hyperlipidemia caused by elevated triglycerides.

3. Ezetimibe Tablets: Ezetimibe tablets are representative drugs of cholesterol absorption inhibitors, primarily lowering lipids by inhibiting the intestinal absorption of cholesterol. They can be used alone or in combination with statins to enhance lipid control.

4. Inositol Nicotinate Tablets: These can lower plasma triglycerides and low-density lipoprotein cholesterol levels, thereby achieving lipid-lowering effects. They have certain application value in the treatment of hypertriglyceridemia or mixed hyperlipidemia.

5. Rosuvastatin Calcium Tablets: Its lipid-lowering mechanism is similar to that of atorvastatin calcium tablets, namely by inhibiting cholesterol synthesis to reduce blood lipids. Rosuvastatin is widely used in clinical settings for treating patients with hyperlipidemia and coronary atherosclerotic heart disease, offering good efficacy and safety.

Patients should maintain good living habits and healthy, scientific dietary habits in daily life and actively adjust their physical condition to improve treatment effectiveness when managing diseases.