Can fatty liver cause elevated indirect bilirubin levels?
Dec 12, 2024
Source: Cainiu Health
Dr. Shen Yonghua
Introduction
In general, whether fatty liver disease causes an increase in indirect bilirubin mainly depends on the specific type of fatty liver and the severity of the condition. If it is non-alcoholic steatohepatitis (NASH), it may lead to elevated indirect bilirubin levels; however, if it is simple fatty liver, it may not cause an increase in indirect bilirubin. If you experience any discomfort, it is recommended to seek medical attention promptly.
Generally, whether fatty liver causes elevated indirect bilirubin levels mainly depends on the specific type of fatty liver and the severity of the condition. If it is non-alcoholic steatohepatitis, indirect bilirubin levels may increase; however, if it is simple fatty liver, indirect bilirubin levels may not rise. If you experience any discomfort, timely medical consultation is recommended. Detailed analysis is as follows:
If the condition is non-alcoholic steatohepatitis, there may be hepatocyte injury, impaired bile excretion, reduced liver function, and metabolic abnormalities, which can lead to liver dysfunction affecting the metabolism and excretion of bilirubin. In such cases, elevated indirect bilirubin levels may occur, often accompanied by increased transaminase levels.
If the condition is simple fatty liver, where fat accumulates in the liver without significant inflammatory response, indirect bilirubin levels typically do not rise directly. Elevation of indirect bilirubin is more closely related to hepatic metabolic dysfunction, and since liver function in simple fatty liver may not be severely affected, indirect bilirubin levels may remain normal.
Patients with fatty liver should pay attention to improving dietary habits in daily life, avoid consuming high-fat, high-calorie, high-sugar, and high-cholesterol foods, engage in moderate physical activity, and undergo regular medical check-ups.
