What are the efficacy and effects of Benorilate Tablets?
Dec 12, 2024
Source: Cainiu Health
Dr. Yang Ziqi
Introduction
In general, Benorilate Tablets are an over-the-counter medication, primarily composed of aspirin and paracetamol, with good antipyretic, analgesic, anti-inflammatory effects. Benorilate Tablets have functions and indications including pain relief, fever reduction, anti-inflammation, anti-rheumatism, and gastrointestinal protection. Close observation of bodily reactions is necessary during use, and if abnormalities occur, administration should be stopped promptly and medical advice sought.
Generally, Benorilate Tablets are mainly composed of aspirin and paracetamol, possessing good antipyretic, analgesic, and anti-inflammatory effects. Benorilate Tablets can relieve pain, reduce body temperature, provide anti-inflammatory and anti-rheumatic effects, and protect the gastrointestinal tract. Specific functions and effects are as follows:
1. Pain Relief
Benorilate Tablets have analgesic properties. By inhibiting the synthesis and release of prostaglandins, they reduce the transmission of pain signals, thereby alleviating pain caused by various conditions, such as headaches, joint pain, toothaches, muscle pain, nerve pain, and dysmenorrhea.
2. Temperature Reduction
Benorilate Tablets contain ingredients such as paracetamol and ibuprofen. These components inhibit prostaglandin synthesis in the body, lower the temperature set point of the body's thermoregulatory center, and thus reduce body temperature. Benorilate Tablets can effectively alleviate fever symptoms caused by colds and influenza.
3. Anti-Inflammatory
Benorilate Tablets exert anti-inflammatory effects by inhibiting cyclooxygenase in the arachidonic acid metabolic pathway, blocking the conversion of PGH2 into pro-inflammatory mediators such as PGE2 and PGF2α. They are commonly used in the treatment of inflammatory diseases such as rheumatoid arthritis and ankylosing spondylitis, helping to reduce patients' inflammatory symptoms.
4. Anti-Rheumatic
The paracetamol and ibuprofen components in Benorilate Tablets can also inhibit immune cell activation and inflammatory factors, thereby achieving anti-rheumatic effects. Benorilate Tablets can alleviate symptoms of autoimmune diseases such as rheumatoid arthritis to a certain extent.
5. Gastrointestinal Protection
Compared with traditional non-steroidal anti-inflammatory drugs (NSAIDs), Benorilate Tablets cause less gastrointestinal irritation and are less likely to damage the gastric mucosa. This is because Benorilate is not immediately hydrolyzed in the stomach after oral administration, but is absorbed and broken down into aspirin and paracetamol in the intestines, thereby reducing the risk of direct damage to the gastric lining.
Benorilate Tablets may cause side effects such as nausea, vomiting, and rash. Long-term and excessive use may lead to liver and kidney function damage. Therefore, physical reactions should be closely monitored during use, and if any abnormalities occur, the medication should be discontinued promptly and medical advice sought.
