Is it necessary to receive the rabies vaccine serum protein?

Dec 20, 2024 Source: Cainiu Health
Dr. Yang Ziqi
Introduction
Under normal circumstances, rabies vaccine serum protein refers to the rabies vaccine and rabies immunoglobulin. Rabies immunoglobulin is a type of passive immunizing agent primarily used for individuals with category III rabies exposure, as well as for those with severe immunodeficiency, long-term and high-dose use of immunosuppressive agents, and category II exposure involving the head or face. Individuals with the aforementioned conditions may receive the immunoglobulin injection.

Generally speaking, rabies vaccine serum protein refers to rabies immune globulin. Whether rabies immune globulin is needed depends on the specific circumstances. If the exposure is mild, it usually isn't necessary; however, if the exposure is severe, it may be required. If discomfort occurs, it is recommended to seek medical attention at a hospital promptly and undergo standardized treatment under the guidance of a physician. Detailed analysis is as follows:

If the exposure is relatively minor, such as being licked by a dog on broken skin or sustaining a bite or scratch wound that is small, only slightly bleeding or reddened, and located away from the head, vaccination with rabies vaccine alone may be sufficient, without the need for rabies vaccine serum protein injection.

If bitten or scratched severely by an animal, such as a dog or cat, suspected of carrying the rabies virus, particularly when the wound is deep and large, or located on the head, neck, or other areas close to the central nervous system, the risk of rabies infection is significantly higher. Injection of rabies immune globulin can rapidly provide passive immunity, offering protection before the vaccine stimulates antibody production. In such cases, administration of rabies immune globulin is highly necessary.

After being bitten by an animal, one should seek timely medical attention, where a professional physician can perform a risk assessment and provide the most appropriate management recommendations.