Is it serious if TCT shows koilocytes?

Dec 23, 2024 Source: Cainiu Health
Dr. Zhang Lu
Introduction
Under normal circumstances, TCT refers to liquid-based thin-layer cytology testing. "Koilocytes" refer to superficial squamous cells that gradually form as a result of accelerated maturation of infected cells after human papillomavirus (HPV) infection. Whether koilocytes are visible and the severity observed in liquid-based thin-layer cytology testing mainly depend on the type of HPV infection. Infections caused by low-risk types of HPV are generally not severe.

Generally, TCT refers to liquid-based thin-layer cytology testing. "Koilocytes" refer to superficial squamous cells that form gradually due to accelerated maturation of infected cells after human papillomavirus (HPV) infection. Whether the presence of koilocytes observed during liquid-based thin-layer cytology testing is serious mainly depends on the type of HPV infection. Low-risk HPV infections generally are not serious, whereas high-risk HPV infections are considered more severe. If any discomfort occurs, timely medical consultation is recommended. Detailed explanations are as follows:

If HPV testing results indicate a low-risk HPV infection, it may cause only mild cellular changes. In such cases, the presence of koilocytes does not necessarily indicate a severe disease. Doctors may recommend regular follow-up observation rather than immediate treatment.

If HPV testing results show a high-risk HPV infection and combined with liquid-based thin-layer cytology testing and cervical biopsy results, cervical precancerous lesions—especially high-grade precancerous lesions—are detected, the condition is considered more serious.

In daily life, maintaining a healthy lifestyle and undergoing regular follow-up examinations at the hospital can help maintain overall health.