Is it serious if TCT shows koilocytes?
Generally, TCT refers to liquid-based thin-layer cytology testing. "Koilocytes" refer to superficial squamous cells that form gradually due to accelerated maturation of infected cells after human papillomavirus (HPV) infection. Whether the presence of koilocytes observed during liquid-based thin-layer cytology testing is serious mainly depends on the type of HPV infection. Low-risk HPV infections generally are not serious, whereas high-risk HPV infections are considered more severe. If any discomfort occurs, timely medical consultation is recommended. Detailed explanations are as follows:
If HPV testing results indicate a low-risk HPV infection, it may cause only mild cellular changes. In such cases, the presence of koilocytes does not necessarily indicate a severe disease. Doctors may recommend regular follow-up observation rather than immediate treatment.
If HPV testing results show a high-risk HPV infection and combined with liquid-based thin-layer cytology testing and cervical biopsy results, cervical precancerous lesions—especially high-grade precancerous lesions—are detected, the condition is considered more serious.
In daily life, maintaining a healthy lifestyle and undergoing regular follow-up examinations at the hospital can help maintain overall health.