What are the symptoms of hepatosplenomegaly?

Generally, hepatosplenomegaly may present symptoms such as abdominal discomfort, loss of appetite, jaundice, coagulation disorders, and abdominal mass. Detailed analysis is as follows:

1. Abdominal Discomfort

As the liver and spleen are located in the upper abdomen, when enlarged, they can compress the gastrointestinal tract and other organs, causing symptoms such as abdominal distension and dull pain. In addition, nausea, vomiting, and diarrhea may also occur as digestive system symptoms.

2. Loss of Appetite

Impaired liver function can affect digestion and nutrient absorption, leading to symptoms such as decreased appetite and weight loss. At the same time, insufficient bile secretion can hinder normal fat metabolism, easily causing problems such as steatorrhea.

3. Jaundice

Liver cell damage can lead to elevated serum bilirubin levels, resulting in yellowing of the skin and mucous membranes, known as jaundice. In severe cases, symptoms such as darkened urine and yellowing of the sclera may also appear.

4. Coagulation Disorders

Abnormal liver function may reduce the synthesis of coagulation factors, increasing the risk of bleeding. Common manifestations include subcutaneous bruising, epistaxis, gingival bleeding, and menorrhagia. If esophagogastric varices are present and rupture occurs, severe complications such as hematemesis and melena may develop.

5. Abdominal Mass

When the liver and spleen enlarge significantly, firm masses with limited mobility and generally no obvious tenderness can be palpated in the left and right upper quadrants of the abdomen.

The symptoms of hepatosplenomegaly may vary among individuals and may be accompanied by other complications. Therefore, when the above symptoms appear, timely medical consultation and detailed examinations are necessary for accurate diagnosis and appropriate treatment measures.