What does the three-item liver function test check?

Jan 03, 2025 Source: Cainiu Health
Dr. Gao Jun
Introduction
The three main indicators for liver function tests are alanine aminotransferase (ALT), aspartate aminotransferase (AST), and gamma-glutamyl transferase (GGT). It is important to maintain a balanced diet in daily life, avoiding excessive intake of fat, sugar, and salt, while consuming more foods rich in vitamins and minerals. Additionally, engaging in moderate aerobic exercise can help promote metabolism and blood circulation, thereby reducing the burden on the liver.

Generally, the three main indicators for liver function tests are alanine aminotransferase (ALT), aspartate aminotransferase (AST), and gamma-glutamyl transferase (GGT). Detailed analysis is as follows:

1. Alanine Aminotransferase (ALT)

ALT primarily exists in liver cells and is an enzyme released into the bloodstream when liver cells are damaged. Under normal circumstances, ALT concentration in the blood is very low. When liver cells are damaged, its concentration rises significantly, making it an important indicator of liver cell injury.

2. Aspartate Aminotransferase (AST)

AST also exists within liver cells but is additionally found in the myocardium and skeletal muscles. When liver cells are damaged, AST is released into the bloodstream, and the degree of elevation in its concentration reflects the severity of liver cell damage.

3. Gamma-Glutamyl Transferase (GGT)

GGT mainly exists in tissues such as the liver and kidneys and participates in the metabolic process of glutathione. Elevated GGT levels may be associated with liver disease, biliary obstruction, alcohol consumption, and other factors.

In daily life, maintaining a balanced diet is important. Avoid excessive intake of fats, sugars, and salts, and consume more foods rich in vitamins and minerals. At the same time, engaging in moderate aerobic exercise, such as walking or jogging, can help promote metabolism and blood circulation, thereby reducing the burden on the liver.