Is Marfan syndrome congenital or acquired?

Marfan syndrome, also known as Marfan's syndrome, is generally a congenital disease. If necessary, timely medical consultation and treatment guided by professional physicians are recommended. Detailed analysis is as follows:

Marfan syndrome is an autosomal dominant genetic disorder caused by gene mutations. The disease results from defects in the fibrillin-1 gene, which lead to excessive stretching of connective tissues, subsequently causing the condition. As this genetic defect is usually congenital—meaning individuals are born with the defective gene—Marfan syndrome is considered a congenital disorder.

Furthermore, Marfan syndrome exhibits a clear genetic predisposition, with family members of affected individuals often displaying similar symptoms. This familial clustering further supports the congenital nature of Marfan syndrome. Therefore, if someone in the family has Marfan syndrome, the risk of the condition in offspring is increased.

It is recommended that individuals with Marfan syndrome undergo regular medical check-ups to promptly detect and treat potential cardiovascular complications, such as aortic aneurysms and dissections.